Key result
Diastolic blood pressure ≥90 mmHg was significantly associated with a 3.02-fold increased odds of a first ischemic stroke in hypertensive patients compared to diastolic blood pressure <90 mmHg.
Why the study?
The study was conducted to determine the relationship between diastolic blood pressure and the first occurrence of ischemic stroke in hypertensive patients.
Does diastolic blood pressure ≥90 mmHg increase the risk of first ischemic stroke in hypertensive patients?
Case-Control (n=94)
Yes
Does diastolic blood pressure ≥90 mmHg increase the risk of first ischemic stroke in hypertensive patients?
In hypertensive patients, a diastolic blood pressure of ≥90 mmHg is associated with a 3-fold increased odds of experiencing a first ischemic stroke.
Answers are grounded in this paper and cite their sources.
DBP ≥90 mmHg triples odds of first ischemic stroke; hypothesis-generating association in small case-control study requires prospective confirmation before practice implications.
BACKGROUND: Stroke has been the second leading cause of death and the third cause of disability worldwide. A record of hypertension and an increase in diastolic blood pressure (DBP) after the first stroke were associated with an increased risk of a second stroke. DBP has historically been considered as the leading cause of cardiac arrest in adults with hypertension. In the previous studies, it was found a relationship between DBP with stroke and functional outcomes. AIM: This research was carried out to determine the relationship between DBP and the event of ischemic stroke for the 1st time in hypertension patients. METHODS: This research is a case–control that was selected using a consecutive sampling technique, where 47 hypertensive patients with ischemic stroke as the case group were matched with 47 hypertensive patients without stroke as the control group. The research was conducted at H. Adam Malik Hospital, Medan and a network hospital. RESULTS: In this research, most samples in the case and control groups were men with 30 subjects (63.8%) with a mean age value of 58.11 ± 10.85 years. At TDD ≥90 mmHg, 34 subjects (72.3%) had ischemic stroke and 21 subjects (44.7%) did not. At TDD <90 mmHg, the percentage of ischemic stroke was 13 subjects (27.7%) and 26 subjects (55.3%) were non-ischemic stroke with p = 0.006, OR = 3.02. CONCLUSION: There is a significantly close relationship between diastolic blood pressure and the event of ischemic stroke.
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Surbakti et al. (2022) conducted a case-control in Hypertension with first ischemic stroke (n=94). Diastolic blood pressure ≥90 mmHg vs. Diastolic blood pressure <90 mmHg was evaluated on First ischemic stroke (OR 3.02, 95% CI 1.37-7.65, p=0.006). Diastolic blood pressure ≥90 mmHg was significantly associated with a 3.02-fold increased odds of a first ischemic stroke in hypertensive patients compared to diastolic blood pressure <90 mmHg.
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