Therapeutic hypothermia with a novel surface cooling device improves neurologic outcome after prolonged cardiac arrest in swine*

Andreas Janata; Wolfgang Weihs; Keywan Bayegan; Alexandra Schratter; Michael Hölzer; Wilhelm Behringer; Robert B. Schock; Udo Losert; Gregor Springler; Peter Schmidt; Fritz Sterz

doi:10.1097/ccm.0b013e318165fb33

March 1, 2008Critical Care Medicine

Therapeutic hypothermia with a novel surface cooling device improves neurologic outcome after prolonged cardiac arrest in swine*

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Key Points

The study aims to evaluate the effectiveness of a novel cooling device in inducing mild hypothermia and improving neurologic outcomes after cardiac arrest.
An experimental study involving anesthetized swine subjected to cardiac arrest followed by randomization into hypothermic and control groups.
Hypothermia group cooled from 38.5°C to 33.0°C for 14 hours; assessed neurologic outcomes at day 9.
Group comparisons conducted using Mann-Whitney U test.
All hypothermia group swine achieved overall performance categories score of 1; control had only one achieving score of 1, three with score of 2, and four with score of 3 (p = 0.002).
Neurologic deficit score was significantly lower in the hypothermia group at 0% compared to 39% in the control group (p = 0.001).
No harmful side effects were observed during the intervention.

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Implication

Prospective experimental study shows improved neurologic outcomes in swine with hypothermia after cardiac arrest, suggesting the device's effectiveness.

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Janata et al. (2008) studied this question.

synapsesocial.com/papers/6a637c1d84b804377828bce2 https://doi.org/10.1097/ccm.0b013e318165fb33

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Therapeutic hypothermia with a novel surface cooling device improves neurologic outcome after prolonged cardiac arrest in swine*

Key Points

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Discussion

Cite This Study

Therapeutic hypothermia with a novel surface cooling device improves neurologic outcome after prolonged cardiac arrest in swine*

Key Points

No abstract yet

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Implication

Discussion

Cite This Study

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