Key result
Gold-tip and irrigated catheters achieve identical acute bidirectional block rates in high-power CTI ablation.
Why the study?
High-power strategies have been described to improve lesion efficacy and durability during CTI ablation for typical atrial flutter, but comparative data between catheter strategies were needed.
Does high-power CTI ablation using an 8-mm nonirrigated catheter improve acute bidirectional block and long-term outcomes compared to a 4-mm irrigated catheter in patients with typical atrial flutter?
Cohort (n=253)
No
Does high-power CTI ablation using an 8-mm nonirrigated catheter improve acute bidirectional block and long-term outcomes compared to a 4-mm irrigated catheter in patients with typical atrial flutter?
Absolute Event Rate: 97.8% vs 97.8%
p-value: p=1.000
High-power CTI ablation using either an 8-mm nonirrigated or 4-mm irrigated catheter provides equivalently excellent acute efficacy and long-term freedom from typical atrial flutter.
High acute bidirectional CTI block rates with either catheter in this cohort; leaves open whether randomized trials confirm equivalence for typical atrial flutter.
BACKGROUND: Ablation of the cavo-tricuspid isthmus (CTI) is the standard treatment for typical atrial flutter. High-power strategies have been described to improve lesion efficacy and durability. OBJECTIVE: To compare the acute success, safety, and long-term outcomes of two strategies of high-power CTI ablation using 8-mm gold-tip nonirrigated and 4-mm irrigated-tip catheters. METHODS: This single-center prospective cohort study included 253 patients who underwent CTI ablation. Patients were treated with either an 8-mm gold-tip nonirrigated catheter (60 W, ≥ 30 s) or a 4-mm irrigated catheter (45 W, ≥ 30 s). Procedural outcomes, safety, and long-term follow-up data were assessed. RESULTS: Using a propensity score matching, 180 patients were yielded with a 1:1 ratio. Acute bidirectional CTI block was achieved in 97.8% of the 4-mm group and 97.8% of the 8-mm group (p = 1.000). No major complications were reported. During a median follow-up of 27.7 ± 20.1 months, freedom from atrial arrhythmia was 93.3% in both groups (log rank p value 0.935). No significant differences were observed in atrial fibrillation incidence, pacemaker implantation, or cardiovascular mortality between the groups. CONCLUSION: High-power CTI ablation with both 8-mm gold-tip nonirrigated and 4-mm irrigated catheters is highly effective and safe, providing durable outcomes over long-term follow-up.
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Zaher et al. (2025) conducted a cohort in Typical atrial flutter (n=253). 8-mm gold-tip nonirrigated catheter vs. 4-mm irrigated catheter was evaluated on Acute bidirectional CTI block (p=1.000). High-power CTI ablation achieved identical acute bidirectional block rates (97.8%) with both the 8-mm gold-tip nonirrigated and 4-mm irrigated catheters.
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