Key result
Surgical resection of a right adrenal pheochromocytoma resolved symptoms in a 46-year-old female who initially presented with Takotsubo cardiomyopathy and new-onset diabetes.
Case Report (n=1)
Pheochromocytoma can initially present as Takotsubo cardiomyopathy, which resolves upon surgical resection of the tumor.
Case of Takotsubo with new diabetes highlights possible link; leaves open causal association pending prospective data.
Takotsubo cardiomyopathy, or transient left ventricular apical ballooning or broken heart syndrome, is characterized by excessive sympathetic stimulation induced acute coronary vasospasm. A 46-year-old female presented with polyuria and polydypsia and was diagnosed with new-onset diabetes mellitus, treated with insulin and intravenous fluids. During the hospital stay, she complained of an episode of left-sided chest pain and had mildly elevated cardiac enzymes. EKG showed new ST-segment elevation in V2, V3 leads without reciprocal changes. Her coronary angiogram showed no significant coronary artery stenosis, but severe systolic dysfunction and akinesis of the mid-anterior, anteroapical, mid-inferior and inferoapical segments. Further workup was negative except for plasma metanephrine being elevated. MRI of the abdomen showed a right adrenal mass consistent with pheochromocytoma. Surgical resection of the adrenal mass showed evidence of pheochromocytoma and the patient's symptoms were resolved.
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Gujja et al. (2010) conducted a case report in Takotsubo cardiomyopathy and pheochromocytoma (n=1). Surgical resection of adrenal mass was evaluated on Resolution of symptoms. Surgical resection of a right adrenal pheochromocytoma resolved symptoms in a 46-year-old female who initially presented with Takotsubo cardiomyopathy and new-onset diabetes.
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