This review describes the histologic changes and histogenesis of intimal hyperplasia in vein-to-artery grafts, highlighting the role of intimal smooth-muscle cells in graft failure.
This review summarizes the histologic changes and the role of intimal smooth-muscle cells in vein-to-artery graft failure due to intimal hyperplasia.
This article reviews the success of vein-to-artery grafts and the published data on patency rates and the major causes for graft failure, ie, intimal hyperplasia and atherosclerosis. It concentrates on the histogenesis of intimal hyperplasia and describes the histologic changes that occur in a vein graft after its insertion. The origin and behavior of intimal smooth-muscle cells are discussed in detail, with particular reference to their role in intimal hyperplasia. A brief experimental section is included to show the specific identification of vein-graft intimal smooth-muscle cells using light-microscopic histochemistry and electron microscopy.
Rodney J. Dilley (Wed,) conducted a review in Vein-to-artery grafts and intimal hyperplasia. Vein-to-artery grafts was evaluated. This review describes the histologic changes and histogenesis of intimal hyperplasia in vein-to-artery grafts, highlighting the role of intimal smooth-muscle cells in graft failure.