Key result
Novel oral anticoagulants were associated with a statistically significant greater risk of postoperative hemorrhagic complications compared to traditional oral anticoagulants during Mohs surgery.
Why the study?
Does the use of novel oral anticoagulants increase postoperative hemorrhagic complications compared to traditional oral anticoagulants in patients undergoing Mohs micrographic surgery?
Cohort
No
Does the use of novel oral anticoagulants increase postoperative hemorrhagic complications compared to traditional oral anticoagulants in patients undergoing Mohs micrographic surgery?
Novel oral anticoagulants are associated with a higher risk of postoperative bleeding complications compared to traditional oral anticoagulants in patients undergoing Mohs micrographic surgery.
Quantifies complication rates on novel anticoagulants in MMS; extends observational data but leaves open need for prospective trials.
BACKGROUND: A significant number of patients undergoing Mohs micrographic surgery (MMS) for skin cancer are treated with oral anticoagulants. The incidence of postoperative complications associated with new classes of oral anticoagulants remains largely unknown. OBJECTIVE: To determine the incidence of postoperative complications in patients undergoing MMS on both traditional oral anticoagulants and new novel oral anticoagulants. MATERIALS AND METHODS: A single-center retrospective chart review was performed for all patients treated with oral anticoagulants who underwent MMS between July 1, 2012 and June 30, 2015 at University of California, San Diego. RESULTS: The data from this study demonstrated that patients treated with a novel oral anticoagulant at the time of MMS had a statistically significant greater risk for developing postoperative hemorrhagic complications compared to patients treated with traditional oral anticoagulants. CONCLUSION: Dermatologic surgeons should manage both traditional oral anticoagulants and novel oral anticoagulants in a similar manner. Future studies are warranted.
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Eilers et al. (2017) conducted a cohort in Skin cancer. Novel oral anticoagulants vs. Traditional oral anticoagulants was evaluated on Postoperative hemorrhagic complications. Novel oral anticoagulants were associated with a statistically significant greater risk of postoperative hemorrhagic complications compared to traditional oral anticoagulants during Mohs surgery.
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