Key result
Clopidogrel use in 32 patients undergoing minor excisional cutaneous surgery was not associated with a significant difference in complications compared to 2,073 historical controls.
Why the study?
Does continuing clopidogrel increase the risk of complications in patients undergoing minor excisional cutaneous surgery compared to historical controls?
Population
2,105 patients undergoing surgery for excision of skin or subcutaneous lesions under local anesthesia
Comparison
Clopidogrel continued during surgery vs Historical controls
Design
Cohort
Follow-up
1 to 2 weeks and 3 to 6 months
Authors
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May support continuing clopidogrel for skin surgery; leaves open need for randomized trials before practice change.
Cohort (n=2,105)
Does continuing clopidogrel increase the risk of complications in patients undergoing minor excisional cutaneous surgery compared to historical controls?
Continuing clopidogrel during minor excisional cutaneous surgery appears safe and does not increase the rate of complications compared to historical controls.
Kramer et al. (2010) conducted a cohort in Skin or subcutaneous lesions requiring excision (n=2,105). Clopidogrel vs. Historical controls (including patients taking aspirin, warfarin, and no antiplatelets) was evaluated on Incidence of complications. Clopidogrel use in 32 patients undergoing minor excisional cutaneous surgery was not associated with a significant difference in complications compared to 2,073 historical controls.
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