Key result
Immobilized quaternary ammonium compound coatings were virucidal against influenza A (H1N1) within 2 minutes, but showed no virucidal effect against poliovirus within 6 hours.
Immobilized quaternary ammonium compound coatings rapidly inactivate enveloped influenza A virus but are ineffective against nonenveloped poliovirus.
IQAC surfaces may rapidly reduce enveloped virus transmission risk; leaves open activity against nonenveloped pathogens and clinical translation.
Virucidal activity of immobilized quaternary ammonium compounds (IQACs) coated onto glass and plastic surfaces was tested against enveloped influenza A (H1N1) virus and nonenveloped poliovirus Sabin1. The IQACs tested were virucidal against the influenza virus within 2 min, but no virucidal effect against poliovirus was found in 6 h.
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Tuladhar et al. (2012) studied this question. Immobilized quaternary ammonium compound coatings were virucidal against influenza A (H1N1) within 2 minutes, but showed no virucidal effect against poliovirus within 6 hours.
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