Key result
Impossible mobilization after surgery for proximal femur fracture was associated with a significantly increased risk of 90-day mortality (OR 10.493) compared to full weight-bearing.
Why the study?
Despite improvements in proximal femur fracture management and timing surgery within 24 hours, mortality remains high, prompting an analysis of cofactors influencing 90-day post-surgical mortality.
What factors are associated with 90-day mortality in patients aged ≥ 65 years undergoing surgery for proximal femur fracture?
Cohort (n=734)
No
What factors are associated with 90-day mortality in patients aged ≥ 65 years undergoing surgery for proximal femur fracture?
In older patients undergoing surgery for proximal femur fracture, 90-day mortality remains high (17.6%) and is driven primarily by patient-related factors (age, BMI, comorbidities) and postoperative mobilization rather than surgical or anesthetic timing.
Answers are grounded in this paper and cite their sources.
Should not yet change practice in geriatric hip fracture care; hypothesis-generating for prospective validation of risk stratification.
Background Despite improving the management of proximal femur fractures (PFF) with legal requirements of timing the surgery within 24 h, mortality rates in these patients remain still high. The objective of our study was to analyze potential cofactors which might influence the mortality rate within 90 days after surgery in PFF to avoid adverse events, loss of quality of life and high rates of mortality. Methods In this retrospective, single-center study all patients with PFF aged 65 years and older were included. We recorded gender, age, type of fracture, surgery and anesthesia, time, comorbidities and medication as well as complications and mortality rate at 90 days. Separate logistic regression models were used to assess which parameters were associated with patients’ mortality. The mortality rate was neither associated with timing, time and type of surgery nor time and type of anesthesia, but with higher age (OR 1.08 per year; 95% CI 1.034–1.128), lower BMI (OR 0.915 per kg/m 2 ; 95% CI 0.857–0.978), higher CCI (OR 1.170 per point; 95% CI 1.018–1.345), dementia (OR 2.805; 95% CI 1.616–4.869), non-surgical complications (OR 2.276; 95% CI 1.269–4.083) and if mobilization was impossible (OR 10.493; 95% CI 3.612–30.479). Results We analyzed a total of 734 patients (age ≥ 65 years) who had a PFF in 2019 and 2020 and received surgery. 129 patients (17.6%) died until 90 days at an median age of 89.7 years (range 65–101 years). Conclusion The proportion of patients who died until 90 days after surgery is still high. It is less extend influenced by surgical and anaesthesiologic factors than by patient-related factors like age or lower BMI. Physicians should be aware of the importance of avoiding adverse events and the importance of patients’ mobilization to reduce mortality and improve patients’ outcome.
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Postler et al. (2024) conducted a cohort in Proximal femur fracture (n=734). Impossible mobilization vs. Full weight-bearing was evaluated on 90-day mortality (OR 10.493, 95% CI 3.612-30.479, p=<0.001). Impossible mobilization after surgery for proximal femur fracture was associated with a significantly increased risk of 90-day mortality (OR 10.493) compared to full weight-bearing.
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