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November 21, 2017IEEE Transactions on Neural Systems and Rehabilitation Engineering316 citations

A Novel Multi-Class EEG-Based Sleep Stage Classification System

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PMPejman MemarFFFarhad Faradji

Key Result

A novel multi-class EEG-based sleep stage classification system achieved minimum overall accuracy rates of 95.31% and 86.64% using nested 5-fold and subject cross-validation, respectively.

Key Points

  • This study aims to develop a computer-assisted system for accurately classifying sleep stages from EEG signals.
  • Participants included 25 with sleep-disordered breathing and 20 healthy subjects.
  • EEG signals were decomposed into subband epochs and features were extracted for classification.
  • Random forest classifier was used with nested 5-fold cross-validation for performance evaluation.
  • Achieved overall accuracy rates of 95.31% for nested 5-fold and 86.64% for subject cross-validation.
  • The system demonstrated high sensitivity and specificity, outperforming existing systems.

Structured PICO

P
Population
45 subjects, including 25 with suspected sleep-disordered breathing and 20 healthy individuals, used to evaluate an EEG-based sleep stage classification system.
E
Exposure
Multi-class EEG-based sleep stage classification system using a random forest classifier
O
Outcome
Accuracy, sensitivity, and specificity of sleep stage classificationsurrogate

A novel EEG-based sleep stage classification system using a random forest classifier achieved high accuracy, showing promise for automated sleep monitoring.

Abstract

Sleep stage classification is one of the most critical steps in effective diagnosis and the treatment of sleep-related disorders. Visual inspection undertaken by sleep experts is a time-consuming and burdensome task. A computer-assisted sleep stage classification system is thus essential for both sleep-related disorders diagnosis and sleep monitoring. In this paper, we propose a system to classify the wake and sleep stages with high rates of sensitivity and specificity. The EEG signals of 25 subjects with suspected sleep-disordered breathing, and the EEG signals of 20 healthy subjects from three data sets are used. Every EEG epoch is decomposed into eight subband epochs each of which has a frequency band pertaining to one EEG rhythm (i.e., delta, theta, alpha, sigma, beta 1, beta 2, gamma 1, or gamma 2). Thirteen features are extracted from each subband epoch. Therefore, 104 features are totally obtained for every EEG epoch. The Kruskal-Wallis test is used to examine the significance of the features. Non-significant features are discarded. The minimal-redundancy-maximal-relevance feature selection algorithm is then used to eliminate redundant and irrelevant features. The features selected are classified by a random forest classifier. To set the system parameters and to evaluate the system performance, nested 5-fold cross-validation and subject cross-validation are performed. The performance of our proposed system is evaluated for different multi-class classification problems. The minimum overall accuracy rates obtained are 95.31% and 86.64% for nested 5-fold and subject cross-validation, respectively. The system performance is promising in terms of the accuracy, sensitivity, and specificity rates compared with the ones of the state-of-the-art systems. The proposed system can be used in health care applications with the aim of improving sleep stage classification.

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Cite This Study

Memar et al. (2017) studied Sleep-related disorders (n=45). Multi-Class EEG-Based Sleep Stage Classification System was evaluated on Minimum overall accuracy rates for multi-class classification. A novel multi-class EEG-based sleep stage classification system achieved minimum overall accuracy rates of 95.31% and 86.64% using nested 5-fold and subject cross-validation, respectively.

synapsesocial.com/papers/6a653272f57138304a40e3a5https://doi.org/10.1109/tnsre.2017.2776149
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