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September 1, 2004Obstetrics and Gynecology284 citations

Conservative Versus Extirpative Management in Cases of Placenta Accreta

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GKGilles KayemCDCéline DavyFGFrançois Goffinet

Key Result

Conservative management of placenta accreta by leaving the placenta in situ significantly reduced the hysterectomy rate compared to systematic manual removal (15% vs 84.6%; P<0.001).

Study Design

Type

Cohort (n=33)

Multicenter

No

Structured PICO

Does conservative management reduce maternal morbidity and mortality compared to extirpative management in patients with placenta accreta?

P
Population
33 women with placenta accreta managed at a single tertiary center, comparing conservative management (leaving placenta in situ) versus systematic manual removal.
E
Exposure
Conservative management (leaving the placenta in situ)
C
Comparator
Extirpative management (systematic manual removal of the placenta to leave the uterine cavity empty)
O
Outcome
Maternal morbidity and mortality (need for blood transfusion, hysterectomy, intensive care admission, duration of stay in intensive care, and postpartum endometritis)hard clinical

Leaving placenta accreta in situ significantly reduces the need for hysterectomy and blood transfusions compared to manual removal.

Main Result

Absolute Event Rate: 15% vs 84.6%

p-value: p=<.001

Abstract

OBJECTIVE: To compare the impact of conservative and extirpative strategies for placenta accreta on maternal morbidity and mortality. METHODS: We retrospectively reviewed the medical records of all patients diagnosed with placenta accreta admitted to our tertiary center from January 1993 through December 2002. Two consecutive periods, A and B, were compared. During period A (January 1993 to June 1997), our written protocol called for the systematic manual removal of the placenta, to leave the uterine cavity empty. In period B (July 1997 to December 2002), we changed our policy by leaving the placenta in situ. The following outcomes over the 2 periods were compared: need for blood transfusion, hysterectomy, intensive care admission, duration of stay in intensive care, and postpartum endometritis. RESULTS: Thirty-three cases of placenta accreta were observed among 31,921 deliveries (1.03/1,000). During period B, there was a reduction in the hysterectomy rate (from 11 84.6% to 3 15%; P <.001), the mean number of red blood cells transfused (3,230 +/- 2,170 mL versus 1,560 +/- 1,646 mL; P <.01), and disseminated intravascular coagulation (5 38.5% versus 1 5.0%; P =.02), compared with period A. There were 3 cases of sepsis in period B and none in period A (P =.26). At least 2 women with conservative management subsequently had successful pregnancies. CONCLUSION: Leaving the placenta accreta in situ appears to be a safe alternative to removing the placenta.

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Cite This Study

Kayem et al. (2004) conducted a cohort in Placenta accreta (n=33). Conservative management (leaving placenta in situ) vs. Extirpative management (systematic manual removal of the placenta) was evaluated on Hysterectomy (p=<.001). Conservative management of placenta accreta by leaving the placenta in situ significantly reduced the hysterectomy rate compared to systematic manual removal (15% vs 84.6%; P<0.001).

synapsesocial.com/papers/6a6540e7f57138304a40efeehttps://doi.org/10.1097/01.aog.0000136086.78099.0f
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