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January 1, 1990The Journal of Cell BiologyOpen Access

The majority of type 1 plasminogen activator inhibitor associated with cultured human endothelial cells is located under the cells and is accessible to solution-phase tissue-type plasminogen activator.

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Authors

RSRaymond R. SchleefBoston UniversityTPThomas J. PodorProvidence Health CareEDEimear DunneUniversity College Dublin

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Cite This Study

Schleef et al. (1990) studied this question.

synapsesocial.com/papers/6a6547ed1b122b07e7b2e68ahttps://doi.org/10.1083/jcb.110.1.155
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Purification of a Protein from Bovine Plasma That Binds to Type 1 Plasminogen Activator Inhibitor and Prevents Its Interaction with Extracellular Matrix1989 · 196 citations
  2. 2Cultured endothelial cell monolayers that restrict the transendothelial passage of macromolecules and electrical current1984 · 217 citations
  3. 3Detection of both type 1 and type 2 plasminogen activator inhibitors in human cells1988 · 54 citations
  4. 4Cytokine activation of vascular endothelium. Effects on tissue-type plasminogen activator and type 1 plasminogen activator inhibitor.1988 · 556 citations
  5. 5Purification and characterization of a plasminogen activator inhibitor 1 binding protein from human plasma. Identification as a multimeric form of S protein (vitronectin).1988 · 489 citations