Answers are grounded in this paper and cite their sources.
A cDNA encoding the catalytic subunit of human telomerase was used to generate life-extended derivatives of primary human diploid fibroblasts. The life-extended cells supported efficient human cytomegalovirus (HCMV) replication. A subclone of the life-extended cells was generated containing the HCMV UL82 gene and used to isolate and propagate a virus that exhibited a profound growth defect after infection at a low input multiplicity.
No takes yet. Share an insight, caveat, or question.
Bresnahan et al. (2000) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: