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THE neurofibromatoses consist of two distinct disorders,1 , 2 the genes for which have recently been located on separate chromosomes.3 4 5 6 Neurofibromatosis 1, also called von Recklinghausen's neurofibromatosis, affects approximately 100,000 people in the United States. It is a common and potentially serious inherited disorder of the human nervous system.1 Neurofibromatosis 2, also known as bilateral acoustic neurofibromatosis, affects several thousand Americans and has a molecular origin similar to that of some of the common sporadically occurring tumors of the nervous system — meningiomas, schwannomas, neurofibromas, and possibly gliomas.3 This review discusses the clinical features, diagnostic advances, treatment dilemmas, and basic research findings . . .
Martuza et al. (Thu,) studied this question.