Key result
Overproduction of an 85-kD yeast actin-binding protein caused a reorganization of the actin cytoskeleton, dramatically affecting the budding pattern and spatial growth organization of the yeast cell.
Identification and overproduction of an 85-kD yeast actin-binding protein demonstrates its role as a determinant of growth sites and morphogenesis.
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May guide cytoskeletal studies in cardiomyocytes; leaves open conservation and clinical relevance in humans.
Drubin et al. (1988) studied this question. Overproduction of 85-kD actin-binding protein was evaluated on Reorganization of the actin cytoskeleton, budding pattern, and spatial growth organization. Overproduction of an 85-kD yeast actin-binding protein caused a reorganization of the actin cytoskeleton, dramatically affecting the budding pattern and spatial growth organization of the yeast cell.
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