Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 12, 2001Proceedings of the National Academy of SciencesOpen Access

Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A / DSHP / SAP

View Full Paper
Ask AI
Bookmark
Share

Authors

MCMichael J. CzarCarilion New River Valley Medical CenterEKEllen N. KershCenters for Disease Control and PreventionLMLilia A. MijaresNational Institutes of Health

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Czar et al. (2001) studied this question.

synapsesocial.com/papers/6a658d982a5a659968b69eb3https://doi.org/10.1073/pnas.131193098
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Epstein--Barr Virus-Negative Boys With Non-Hodgkin Lymphoma Are Mutated in the Sh2D1A Gene, as Are Patients With X-Linked Lymphoproliferative Disease (XLP)1999 · 108 citations
  2. 2Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence.1984 · 807 citations
  3. 3Immunoglobulin class and subclass deficiencies prior to Epstein‐Barr virus infection in males with X‐linked lymphoproliferative disease1991 · 72 citations
  4. 4Engagement of the signaling lymphocytic activation molecule (SLAM) on activated T cells results in IL-2-independent, cyclosporin A-sensitive T cell proliferation and IFN-gamma production1997 · 164 citations
  5. 5Potential pathways for regulation of NK and T cell responses: differential X-linked lymphoproliferative syndrome gene product SAP interactions with SLAM and 2B42000 · 105 citations