Key result
Moxonidine is a centrally acting antihypertensive agent that lowers blood pressure, improves metabolic parameters, and offers target-organ protection, but increases mortality in advanced heart failure.
This review highlights moxonidine as an effective centrally acting antihypertensive with additional metabolic and target-organ benefits.
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Moxonidine may offer metabolic and organ-protective benefits in hypertension; leaves open confirmation in prospective randomized trials.
Savopoulos et al. (2013) conducted a review in Hypertension, metabolic syndrome, and heart failure. Moxonidine was evaluated. Moxonidine is a centrally acting antihypertensive agent that lowers blood pressure, improves metabolic parameters, and offers target-organ protection, but increases mortality in advanced heart failure.
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