January 1, 2017Chemical Communications

Detection of N ⁶ -methyladenosine based on the methyl-sensitivity of MazF RNA endonuclease

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Abstract

-methyladenosine (m6A), representing the first m6A-sensitive RNA cleavage enzyme. The methyl-sensitivity of MazF allowed simple analyses of both m6A demethylase and methyltransferase activity. Furthermore, the approach could be used for inhibitor screening.

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Imanishi et al. (2017) studied this question.

synapsesocial.com/papers/6a65982e03c0fc50d5d69c44 https://doi.org/10.1039/c7cc07699a

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Detection of N ⁶ -methyladenosine based on the methyl-sensitivity of MazF RNA endonuclease

Abstract

Discussion

Cite This Study

Detection of N ⁶ -methyladenosine based on the methyl-sensitivity of MazF RNA endonuclease

Abstract

Discussion

Cite This Study

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