Correlation of apparent diffusion coefficient ratio on 3.0 T MRI with prostate cancer Gleason score

INTRODUCTION: on Diffusion MRI to discriminate between benign and malignant lesions of Prostate. METHODS: values were compared with the biopsy result. Data was analysed using independent samples T-test, Spearman correlation, intra-class correlation coefficient (ICC) and Receiver operating characteristic (ROC) curve. RESULTS: value when discriminating Gleason 6 from Gleason ≥7 tumours. Inter-observer reliability in the calculation of ADC ratios was excellent, with ICC of 0.964. CONCLUSION: is a reliable and reproducible tool in quantification of diffusion restriction for clinically significant prostate cancer foci.