Comparative efficacy and safety of oral pharmacological and complementary interventions for premenstrual syndrome: a protocol for a systematic review and a network meta-analysis
Systematic review compares efficacy and safety of pharmacological and complementary interventions for premenstrual syndrome, indicating necessary clinical insights.
Key Points
To compare the efficacy and safety of oral pharmacological and complementary interventions for premenstrual syndrome (PMS) through a network meta-analysis.
Conduct a network meta-analysis including all available randomized controlled trials for PMS treatments.
Assess primary outcomes of symptom intensity and interference, along with secondary outcomes of psychological and somatic symptom intensity.
Evaluate safety based on adverse events and dropout rates using the Cochrane risk of bias assessment tool.
No numerical results available yet as the study is still in protocol phase.
Aim to provide comparative analysis of available treatment options.
First network meta-analysis focused solely on PMS interventions.