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July 26, 2026PLoS ONEOpen Access

Patterns of inpatient antibiotic use and antimicrobial resistance in the surgical wards of a Ugandan tertiary hospital: A mixed methods study

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Authors

FMFiona Mutesi MagololoDBDathan ByonanebyeFDFlavia Dhikusooka

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Overview

Mixed methods study assesses antibiotic use and antimicrobial resistance patterns in surgical wards, indicating urgent interventions needed.

Key Points

  • The study aims to assess patterns of inpatient antibiotic use and antimicrobial resistance in surgical wards.
  • Convergent mixed methods design including quantitative point prevalence surveys and qualitative in-depth interviews.
  • Quantitative data analyzed using R and STATA; qualitative data coded and analyzed with NVivo 12.
  • Sample included 303 surgical inpatients with a focus on prescribing practices.
  • 63.7% of inpatients received at least one antibiotic prescription, primarily for surgical prophylaxis.
  • Ceftriaxone was the most prescribed at 31.7%, followed by metronidazole at 23.5%.
  • Watch category antibiotics were used in over half of the cases (54.1%), within a context of high antimicrobial resistance.

Cite This Study

Magololo et al. (2026) studied this question.

synapsesocial.com/papers/6a65a825d3aea3239cd78933https://doi.org/10.1371/journal.pone.0352983
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Antimicrobial Prescribing Practices for Surgical Prophylaxis in Caesarean Sections at Kawempe National Referral Hospital, Kampala, Uganda2026
  2. 2Pattern of Peri-Operative Antibiotic Use among Surgical Patients in a Regional Referral and Teaching Hospital in Uganda2020 · 11 citations
  3. 3Prescription Practices and Usage of Antimicrobials in a Tertiary Teaching Hospital in Rwanda: A Call for Antimicrobial Stewardship2024 · 2 citations
  4. 4Optimizing Surgical Prophylaxis: An Audit of Antibiotic Use and Guideline Adherence in a Tertiary Care Hospital with Focus on Antimicrobial Stewardship2025
  5. 5ANTIBIOTIC PRESCRIBING PRACTICES AMONG HOSPITALIZED PATIENTS AT A NATIONAL ANTIMICROBIAL CONSUMPTION NETWORK SITE IN NORTH INDIA: A WHO POINT PREVALENCE SURVEY2025