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July 26, 2026Regional Anesthesia & Pain Medicine

Longitudinal outcomes following temporary 60-day percutaneous peripheral nerve stimulation for chronic pain: a retrospective analysis

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Authors

MCMonping ChiangMSM P SmithJKJay Karri

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Overview

Retrospective cohort study evaluates pain response and opioid use in patients with chronic pain after PNS, suggesting further exploration is needed.

Key Points

  • This study aims to evaluate the effectiveness of temporary percutaneous peripheral nerve stimulation for chronic pain management through longitudinal outcomes.
  • Retrospective cohort study of 125 patients treated with 60-day PNS at two hospitals from April 2021 to September 2025.
  • Primary outcome measured was pain reduction defined as ≥30% decrease in Numerical Rating Scale score postprocedure.
  • Analyses included longitudinal pain trajectories and sensitivity assessments for responder rates under different definitions.
  • 24% of patients achieved ≥30% pain reduction from baseline to median postprocedural NRS score.
  • Responder rates varied from 8% to 14% based on sensitivity analyses and pain assessment methods.
  • Lead complications were more frequent among non-responders, and mental health comorbidities were high in the studied population.

Cite This Study

Chiang et al. (2026) studied this question.

synapsesocial.com/papers/6a65a8c9d3aea3239cd78faehttps://doi.org/10.1136/rapm-2026-108123
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Economic Costs of Chronic Pain—United States, 20212025 · 39 citations
  2. 2Pain intensity and opioid consumption after temporary and permanent peripheral nerve stimulation: a 2-year multicenter analysis2024 · 17 citations
  3. 3Randomized Placebo-Controlled Trial of 60-Day Percutaneous Peripheral Nerve Stimulation Treatment Indicates Relief of Persistent Postoperative Pain, and Improved Function After Knee Replacement2024 · 32 citations
  4. 4Retrospective Evaluation of Bipolar Peripheral Nerve Stimulation for Nociceptive and Neuropathic Pain: A Pilot Study2024 · 4 citations
  5. 5Percutaneous 60-day peripheral nerve stimulation implant provides sustained relief of chronic pain following amputation: 12-month follow-up of a randomized, double-blind, placebo-controlled trial2019 · 115 citations