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July 24, 2026Journal of the Anus Rectum and ColonOpen Access

Successful Salvage Underwater Endoscopic Mucosal Resection for Early Colorectal Cancer with Unclear Horizontal and Vertical Margin after Cold Snare Polypectomy: Two Case Reports

Fumihiko Nakamura Kentaro Ishii Masahiko Kuroda Yukako Nemoto

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Key Points

The aim is to address early colorectal cancer cases with unclear margins following cold snare polypectomy.
Two cases of early colorectal cancer with unclear margins after cold snare polypectomy were treated.
Underwater endoscopic mucosal resection was performed as a salvage technique.
Both cases successfully completed underwater endoscopic mucosal resection with clear margins.
The technique demonstrated effectiveness in managing early colorectal cancer with previously uncertain margins.

Implication

Case reports demonstrate effective salvage intervention for unclear margins after cold snare polypectomy, suggesting its viability.

Abstract

We sometimes encounter a case of early colorectal cancer with positive or unidentified margin after cold snare polypectomy (CSP).

Discussion

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Cite This Study

Nakamura et al. (2026) studied this question.

synapsesocial.com/papers/6a67007840bca442e0d4a2f7 https://doi.org/10.23922/jarc.2025-098

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Cold snare polypectomy versus cold endoscopic mucosal resection for small colorectal polyps: a meta-analysis of randomized controlled trials2024 · 7 citations
2Adverse events after different endoscopic resection procedures for small and intermediate-sized colorectal polyps2024
3Cold and Hot Snaring for Colorectal PolypsOriginal Research · 2026
4Survival and Endoscopic/Clinical Features of Patients with Colorectal Cancer Resected by Cold Snare Polypectomy: The Importance of Chronic Kidney Disease2024
5Risk factors for unclear margin in cold snare polypectomy for colorectal polyp2024

More related papers

Updates in the endoscopic management of colorectal polyps2025
Cold Snare Polypectomy and Cold Endoscopic Mucosal Resection Versus Hot Endoscopic Mucosal Resection for Intermediate‐Size Sessile Serrated Lesions: A Randomized Controlled Trial2026
Histopathologic outcomes comparison between cold snare polypectomy and cold snare EMR for colorectal polyps: a full-thickness serial sectioning analysis2026

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