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This research investigates the effectiveness of hydroxyurea in reducing complications associated with haemoglobin SC disease.

Hydroxyurea (hydroxycarbamide) in haemoglobin SC disease: Moving from therapeutic hesitation to evidence‐guided care

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Retrospective study evaluates hydroxyurea's benefits in haemoglobin SC disease, indicating significant treatment advantages.

This research investigates the effectiveness of hydroxyurea in reducing complications associated with haemoglobin SC disease.
Retrospective analysis involving adults with haemoglobin SC disease
Assessment of crisis events and adverse effects related to hydroxyurea
Focus on prescription-renewal barriers and treatment adherence
Hydroxyurea use led to a significant reduction in vaso-occlusive crisis composite events
Most adverse events reported were mild, with no serious complications linked to hyperviscosity
Emphasis on the challenges in patient adherence and renewal of prescriptions for routine care

Tahereh Setayesh (2026) studied this question.

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