Left atrial volume as an index ofleft atrial size: a population-based study
Key result
Left atrial volume indexed to body surface area was more strongly associated with cardiovascular disease than left atrial dimension, with fair agreement between the indexes (kappa = 0.53).
Why the study?
Increased left atrial dimension measured by M-mode echocardiography is a known risk factor for atrial fibrillation, stroke, and death, prompting evaluation of left atrial volume as an index of atrial size.
Population
2,042 residents of Olmsted County, Minnesota, age >=45 years
Comparison
LAV vs LAD
Design
Population-based study
Authors
Discussion
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Implication
Population-based study examines the relationship between left atrial volume and atrial size, indicating its significance in cardiovascular health.
Key Points
- The study aims to evaluate the association between left atrial volume and left atrial size in a population-based cohort.
- Analyzed data from a population-based cohort study
- Measured left atrial volume using echocardiography
- Statistical analysis to assess relationships between variables.
- Significant correlation found between left atrial volume and atrial size (p<0.001)
- Higher left atrial volume associated with increased risk of cardiovascular events.
- Findings suggest left atrial volume is an important marker for atrial health.
Study Design
Type
Cross-Sectional (n=2,042)
Multicenter
No
PICO
P
Population
2,042 residents of Olmsted County, Minnesota, aged ≥45 years, who underwent Doppler echocardiography to assess left atrial size.
E
Exposure / Comparator
Left atrial volume (LAV) vs Left atrial dimension (LAD)
O
Primary Outcome
Agreement between left atrial volume and left atrial dimension indexes — kappa 0.53
Main Result
Effect estimate: kappa 0.53
Cite This Study
Pritchett et al. (2003) conducted a cross-sectional in General population (n=2,042). Left atrial volume (LAV) vs. Left atrial dimension (LAD) was evaluated on Agreement between left atrial volume and left atrial dimension indexes (kappa 0.53). Left atrial volume indexed to body surface area was more strongly associated with cardiovascular disease than left atrial dimension, with fair agreement between the indexes (kappa = 0.53).