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July 29, 2026Portal hypertension & cirrhosisOpen Access

Advances in Viral Markers for Predicting Functional Cure of Chronic Hepatitis B

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Authors

XLXinrong LuXYX L YangQOQishui Ou

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Overview

Review evaluates viral markers predicting functional cure in chronic hepatitis B, indicating better treatment strategies.

Key Points

  • This review aims to summarize recent advancements in predicting functional cure through viral markers in chronic hepatitis B.
  • Evaluated predictive performance of viral markers in chronic hepatitis B
  • Assessed standard clinical assays for quantifying hepatitis B virus
  • Discussed combined regimens of nucleos(t)ide analogues and pegylated interferon‐α
  • Combined treatments improve hepatitis B surface antigen seroclearance rates but few achieve functional cure
  • Quantification of viral markers is essential for predicting outcomes and optimizing treatment strategies
  • Early identification of potential responders could enhance cure rates and decrease costs

Cite This Study

Lu et al. (2026) studied this question.

synapsesocial.com/papers/6a69a2d4c8da07d9defa6c21https://doi.org/10.1002/poh2.70063
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