SEOM‑GETTHI clinical guideline for the practical management of molecular platforms (update 2026)

Identification of molecular alterations in cancer and advances in technology have enhanced the use of molecular alterations for the diagnosis and treatment of cancer in routine clinical practice. Multi-determination platforms are now available in most Spanish hospitals. First developed in 2021, the objective of these clinical practice guidelines is to review the usefulness of molecular platforms and establish usage guidelines to direct their incorporation into clinical practice. Here, we provide updated guidelines, which include the most recent advancements in this area.