Key result
Maximal oxygen consumption was significantly lower in female childhood cancer survivors compared to controls (p < 0.001), a difference not observed in males.
Why the study?
Is there a gender difference in aerobic capacity in adolescents after cure from childhood malignant disease?
Population
35 adolescents cured of childhood malignant disease, who completed their treatment at least two years…
Design
Cross-sectional
Follow-up
At least 2 years post-treatment
Authors
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May indicate sex-specific aerobic deficits warranting attention in survivors; leaves open causal mechanisms and intervention targets.
Cross-Sectional (n=35)
Is there a gender difference in aerobic capacity in adolescents after cure from childhood malignant disease?
p-value: p=< 0.001
Adolescent females cured of childhood cancer exhibit significantly reduced aerobic capacity compared to controls, while anthracycline-related reductions in aerobic capacity were only observed in males.
Matthys et al. (1993) conducted a cross-sectional in Cured from malignant disease in childhood (n=35). Childhood cancer survival vs. Healthy controls was evaluated on Maximal oxygen consumption (ml/min/kg) (p=< 0.001). Maximal oxygen consumption was significantly lower in female childhood cancer survivors compared to controls (p < 0.001), a difference not observed in males.
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