Key result
Medication reconciliation supplemented with medication review significantly reduced the likelihood of 90-day readmission among hospitalized CKD patients compared to usual care (OR 0.41; P=0.002).
Why the study?
Chronic kidney disease, comorbidities, and pill burden expose patients to drug-related problems including medication discrepancies, but the impact of supplemented medication reconciliation on discrepancies and readmissions was unclear.
Does medication reconciliation supplemented with medication review reduce medication discrepancies and 90-day all-cause readmission in hospitalized adult CKD patients?
Does medication reconciliation supplemented with medication review reduce medication discrepancies and 90-day all-cause readmission in hospitalized adult CKD patients?
Medication reconciliation and review by a clinical pharmacist significantly reduces medication discrepancies and 90-day readmission rates in hospitalized CKD patients.
Background Chronic kidney disease (CKD) with its associated comorbidities and pill burden can expose patients to a heightened risk of drug-related problems, including medication discrepancies. This study aimed to evaluate the impact of medication reconciliation supplemented with medication review on the number of medication discrepancies at discharge and all-cause readmission among CKD patients.Methods This was a quasi-experimental trial among adult CKD patients admitted into two major referral hospitals in northern Jordan. Patients in the intervention group received medication reconciliation supplemented with medication review by a clinical pharmacist, while those in the control group received the usual care. The recognised discrepancies were evaluated at admission and at discharge in both groups. Participants were followed for 90-day readmission.Results Among patients in the intervention group, the average number of discrepancies was 2.5 ± 2.2 per CKD patient. Compared to the control group, the reduction in discrepancy numbers between admission and discharge was higher in the intervention group by 1.66 discrepancies. The likelihood of 90-day readmission was significantly lower in the intervention group (OR = 0.41; P = 0.002).Conclusion Supplemented medication reconciliation among CKD patients reveals a favourable impact on medication discrepancies and readmission rates. Optimising medication management during transitions of care can improve overall health outcomes.
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Altawalbeh et al. (2025) studied Chronic kidney disease (CKD). Medication reconciliation supplemented with medication review by a clinical pharmacist vs. Usual care was evaluated on Number of medication discrepancies at discharge and 90-day all-cause readmission (OR 0.41, p=0.002). Medication reconciliation supplemented with medication review significantly reduced the likelihood of 90-day readmission among hospitalized CKD patients compared to usual care (OR 0.41; P=0.002).
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