Key result
High-dose laser balloon ablation (>8.5 W) achieved a higher rate of acute pulmonary vein isolation after a single circular lesion set compared to low-dose ablation (89% vs 69%, P=0.0004).
Why the study?
Does high-dose laser balloon ablation improve acute and chronic success compared to low-dose ablation in patients with atrial fibrillation?
Cohort (n=60)
Does high-dose laser balloon ablation improve acute and chronic success compared to low-dose ablation in patients with atrial fibrillation?
Absolute Event Rate: 89% vs 69%
p-value: p=0.0004
High-dose laser balloon ablation (>8.5 W) significantly improves acute pulmonary vein isolation rates and reduces chronic recurrence compared to low-dose ablation in patients with atrial fibrillation.
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High-dose laser ablation may improve acute PVI success; leaves open optimal energy titration for durable outcomes in AF.
Bordignon et al. (2012) conducted a cohort in Atrial fibrillation (AF) (n=60). High-dose (HD) laser ablation vs. Low-dose (LD) laser ablation (5.5-8.5 W) was evaluated on Acute pulmonary vein isolation (PVI) after a single visually guided circular lesion set (p=0.0004). High-dose laser balloon ablation (>8.5 W) achieved a higher rate of acute pulmonary vein isolation after a single circular lesion set compared to low-dose ablation (89% vs 69%, P=0.0004).
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