Key result
Intravenous allylamine induces early canine coronary artery and aortic lesions marked by glycogen accumulation.
The early lesions of the coronary arteries and aorta in animals given intravenous allylamine are described and are noted to be characterized by glycogen accumulation and by ground substance change indicated by increased PAS-positive material present after incubation with diastase. It is suggested that heterogeneous polysaccharides and/or substances containing 1-2 glycol linkages, other than sulphated acid polysaccharides, may be of importance in the early lesion.
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Conrad et al. (1956) studied Coronary artery and aortic lesions. Intravenous allylamine was evaluated on Histochemical characteristics of early coronary artery and aortic lesions. Intravenous allylamine induced early lesions in canine coronary arteries and aorta, characterized by glycogen accumulation and ground substance change.
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