The Na+/H+ exchanger plays a crucial role in protecting cells from intracellular acidification, but its activation during recovery from ischemia may contribute to calcium overload and reperfusion injury in the myocardium.
Research Article| December 01 1993 The Na+/H+ exchanger: an update on structure, regulation and cardiac physiology L Fliegel; L Fliegel *Departments of Biochemistry and Pediatrics, 417 Heritage Medical Research Building, University of Alberta, Edmonton, Alberta, Canada T6G 2S2 Search for other works by this author on: This Site PubMed Google Scholar O Fröhlich O Fröhlich †Department of Physiology, Emory University School of Medicine, Atlanta, GA 30322, U.S.A. Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1993) 296 (2): 273–285. https://doi.org/10.1042/bj2960273 Views Icon Views Article contents Figures The Na+/H+ exchanger: an update on structure, regulation and cardiac physiology. Biochem J 1 December 1993; 296 (2): 273–285. doi: https://doi.org/10.1042/bj2960273 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1993 The Biochemical Society, London1993 Article PDF first page preview Close Modal You do not currently have access to this content.
Fliegel et al. (Wed,) conducted a review in Intracellular pH regulation and cardiac physiology. Na+/H+ exchanger was evaluated. The Na+/H+ exchanger plays a crucial role in protecting cells from intracellular acidification, but its activation during recovery from ischemia may contribute to calcium overload and reperfusion injury in the myocardium.