Key result
Dyslipidemia linked to ~3.8-fold higher odds of large artery atherosclerosis ischemic stroke.
Observational (n=254)
Yes
Odds Ratio: 3.82 (95% CI 1.76–8.28)
p-value: p=0.001
Lebanon is a developing country where the prevalence of stroke subtypes and their correlation with risk factors have not been studied, even though stroke management is an ongoing major national healthcare challenge. In a retrospective study conducted in two university hospitals, data were collected on all stroke cases admitted in 2012 and 2013. Ischemic strokes were then classified according to a modified TOAST classification. A total of 254 inpatients (mean age 68.41 years ±13.34, 55.1% males) was included in the study; of these, 15% had had a hemorrhagic stroke and was therefore excluded. Conversely to findings from studies in other Arab and Asian countries, where small vessel disease is the most frequent subtype, our study showed a predominance of large artery atherosclerosis (53.5%) which, in comparison with other subtypes, was found to be associated with dyslipidemia (OR= 3.82, 95% CI= [1.76-8.28]; p=0.001). Cardioembolic stroke and small vessel disease were found to be positively associated with aging and living in Beirut, respectively. Larger studies are needed to explain these findings.
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Nathalie Lahoud (2017) conducted an observational in Acute stroke (n=254). Dyslipidemia vs. Absence of dyslipidemia was evaluated on Large artery atherosclerosis ischemic stroke subtype (compared to other subtypes) (OR 3.82, 95% CI 1.76-8.28, p=0.001). Dyslipidemia was significantly associated with the large artery atherosclerosis ischemic stroke subtype compared to other ischemic subtypes (OR 3.82; 95% CI 1.76-8.28; p=0.001).
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