Key result
This historical review traces the 19th and 20th-century discoveries linking arterial stiffness, chronic kidney disease, hypertension, and left ventricular hypertrophy.
This historical review demonstrates that 19th-century physicians had already recognized the pathophysiological links between chronic kidney disease, arterial stiffening, hypertension, and left ventricular hypertrophy.
Historical recognition of these links predates modern eras; leaves open translation to current stiffness-targeted therapies in CKD and hypertension.
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Ferro et al. (2012) conducted a review in Hypertension, arterial stiffness, chronic kidney disease, and left ventricular disease. This historical review traces the 19th and 20th-century discoveries linking arterial stiffness, chronic kidney disease, hypertension, and left ventricular hypertrophy.
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