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Case report reveals pulmonary embolism in adolescents with Sickle Cell Disease during acute chest syndrome, suggesting thromboprophylaxis for COVID-19 related cases.
SARS-CoV-2 causes a hypercoagulable state that predisposes patients to thromboembolic events. We report two adolescents with Sickle Cell Disease (SCD) who developed pulmonary embolism (PE) during acute chest syndrome (ACS) episode associated with a possible SARS-CoV-2 infection. Both SCD and SARS-CoV-2 infection predisposes to thromboembolic disease. Thromboprophylaxis with LMWH should be considered in adolescent with ACS, related or not to COVID-19 disease.
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Demey et al. (2020) studied this question.
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