Key result
Thirst arises from fluid volume deficits and is generated by integrating osmotic and hormonal signals at the lamina terminalis with afferent information from intrathoracic baroreceptors.
Key points are not available for this paper at this time.
Design
Review
Thirst integrates lamina terminalis and baroreceptor signals; leaves open targeted interventions in fluid disorders pending clinical trials.
Thirst is important for maintaining body fluid homeostasis and may arise from deficits in either intracellular or extracellular fluid volume. Neural signals arising from osmotic and hormonal influences on the lamina terminalis may be integrated within the brain, with afferent information relayed from intrathoracic baroreceptors via the hindbrain to generate thirst.
No takes yet. Share an insight, caveat, or question.
McKinley et al. (2004) studied this question. Thirst arises from fluid volume deficits and is generated by integrating osmotic and hormonal signals at the lamina terminalis with afferent information from intrathoracic baroreceptors.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: