Key result
A review of platelet function assays highlights that no single method provides 100% accuracy due to the wide variety of platelet defects, necessitating the use of multiple assays.
This review highlights that no single platelet function assay is 100% accurate, emphasizing the need for multiple assays to accurately assess platelet function.
Clinicians may require multiple assays for reliable platelet assessment; leaves open standardization of optimal testing combinations.
The aim of this article is to review various methods used and started to introduce into practice for determining platelet function, their possibilities, advantages, and disadvantages. Nowadays, in platelet function investigations, devices and their systems with unequal possibilities, operating in different principles, are used. However, because of a wide variety of platelets defects, none of them gives the accuracy of 100%. In order to avoid mistakes, several assays are used. Analysis of platelets function testing is represented in two ways: according to its investigation object and investigation methods and according to the most frequently used platelet function assays. The most important criteria are presented in two different tables.
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Aušra Mongirdienė (2007) conducted a review in Platelet defects. Platelet function assays was evaluated. A review of platelet function assays highlights that no single method provides 100% accuracy due to the wide variety of platelet defects, necessitating the use of multiple assays.
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