Key result
Percutaneous closure of periprosthetic paravalvular leaks was successful in 86% of patients, improving NYHA class in 28 of 35 patients, with 91.9% freedom from cardiac death at 42 months.
Why the study?
Clinically significant periprosthetic paravalvular leak is a serious complication after surgical valve replacement, and percutaneous closure has been utilized as an alternative to surgical repair in high-risk surgical patients.
Observational (n=43)
No
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Randomized trial demonstrates improved clinical outcomes in patients undergoing percutaneous closure of paravalvular leaks, suggesting effective intervention.
Ruiz et al. (2011) conducted an observational in Periprosthetic paravalvular leaks (n=43). Percutaneous device closure was evaluated on Closure success. Percutaneous closure of periprosthetic paravalvular leaks was successful in 86% of patients, improving NYHA class in 28 of 35 patients, with 91.9% freedom from cardiac death at 42 months.
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