Key result
Patients with Brugada syndrome had a higher rate of S-ICD screening failure compared with other cardiac channelopathies (18% vs. 5%, P=0.07), primarily due to high T wave voltages.
Why the study?
Does Brugada syndrome increase the rate of S-ICD sensing screening failure compared to other inherited primary arrhythmia syndromes?
Population
100 patients presenting with inherited primary arrhythmia syndromes, including Brugada syndrome, long-QT…
Comparison
Subcutaneous implantable cardioverter-defibrillat… vs Patients with Brugada syndrome compared to…
Design
Cross-sectional
Authors
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May warrant extra screening caution in Brugada syndrome; leaves open whether syndrome-specific S-ICD criteria are needed.
Observational (n=100)
Does Brugada syndrome increase the rate of S-ICD sensing screening failure compared to other inherited primary arrhythmia syndromes?
Absolute Event Rate: 18% vs 5%
p-value: p=0.07
Patients with Brugada syndrome have a higher rate of S-ICD screening failure compared to other channelopathies, primarily due to high T wave voltages, highlighting the need for careful pre-implantation screening including drug challenge.
Conte et al. (2017) conducted an observational in Inherited primary arrhythmia syndromes (n=100). Brugada syndrome vs. Other cardiac channelopathies (LQTS, ERS, IVF) was evaluated on Inappropriate morphology analysis (S-ICD screening failure) (p=0.07). Patients with Brugada syndrome had a higher rate of S-ICD screening failure compared with other cardiac channelopathies (18% vs. 5%, P=0.07), primarily due to high T wave voltages.
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