Key result
Coronary heart disease is the leading cause of mortality in the Middle East and North Africa, accounting for a quarter of all-cause deaths in 2019, driven by a high burden of undertreated cardiometabolic risk factors.
Why the study?
Coronary heart disease is the leading cause of morbidity, mortality, and disability in the Middle East and North Africa, prompting a review to quantify its burden and highlight regional characteristics, clinical challenges, and future directions.
CHD in the MENA region presents at a younger age and with worse prognosis in women, highlighting the need for improved preventive strategies and access to guideline-recommended therapeutics.
PURPOSE OF REVIEW: Coronary heart disease (CHD) is the leading cause of morbidity, mortality, and disability in the Middle East and North Africa (MENA). While the prevention, diagnosis, and management of CHD have been detailed in international guidelines, we aimed in this review to quantify the pandemic of CHD in the MENA region and highlight regional patient characteristics, clinical challenges, and future directions to optimize CHD care in the region. RECENT FINDINGS: Patients with CHD in the MENA feature younger age at presentation and worse prognosis in women. Despite the high burden of CHD risk factors, many of these factors remain underrecognized, undertreated, and uncontrolled. Additionally, CHD care is hampered by poor patient awareness, inefficient preventive strategies, and limited access to guideline-recommended therapeutics. All stakeholders involved in healthcare should work together to develop and execute strategies aimed at tackling the burden of CHD in the MENA.
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Manla et al. (2023) conducted a review in Coronary heart disease. Coronary heart disease is the leading cause of mortality in the Middle East and North Africa, accounting for a quarter of all-cause deaths in 2019, driven by a high burden of undertreated cardiometabolic risk factors.
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