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January 1, 2021TheranosticsOpen Access

The Polo-like kinase 1 inhibitor onvansertib represents a relevant treatment for head and neck squamous cell carcinoma resistant to cisplatin and radiotherapy

Anaïs Hagege Damien Ambrosetti Julien Boyer Alexandre Bozec J. Doyen Emmanuel Chamorey Xingkang He Isabelle Bourget Julie Rousset Esma Saâda Olivia Rastoin Julien Parola Frédéric Luciano Yihai Cao Gilles Pagès Maeva Dufies

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Abstract

Targeting Plk1 by onvansertib represents a new strategy for HNSCC patients at the diagnosis in combination with reference treatments, or alone as a second line treatment for HNCSCC patients experiencing relapses.

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Hagege et al. (2021) studied this question.

synapsesocial.com/papers/6a6b4d1d2ef98b0efacb515c https://doi.org/10.7150/thno.61711

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