Key result
Annual height loss of ≥0.6 cm was independently associated with a higher risk of MACCE compared to height loss of <0.3 cm (adjusted HR 1.25; 95% CI 1.13-1.40).
Why the study?
Adult height is inversely related to cardiovascular disease, but height also declines with age and differs among individuals, prompting investigation into the link between height loss and cardiovascular disease incidence.
Does height loss predict MACCE incidence in a Korean population?
Cohort (n=127,573)
Does height loss predict MACCE incidence in a Korean population?
Answers are grounded in this paper and cite their sources.
A greater degree of height loss is independently associated with an increased risk of cardiovascular disease in the Korean population.
Background Epidemiologic research has confirmed the inverse relationship between adult height and the incidence of cardiovascular disease (CVD). Height declines with age and its degree differs from person to person. Aim To investigate the association between height loss and CVD incidence. Methods In total, 127 573 ethnically Korean patients were enrolled, and their height (cm) was monitored from 2002 to 2011. The annual height loss (cm/year) was calculated as the difference between the first and the last height measurement within the observation period divided by the number of years. Patients were classified as Group 1 (reference group; height loss: 0 to < 0.3 cm/year; 102 554 patients), Group 2 (height loss: 0.3 to < 0.6 cm/year; 17 324 patients), or Group 3 (height loss: ≥0.6 cm/year; 7695 patients). Results The cumulative MACCE incidence rate was 3.6% for Group 1, 4.5% for Group 2, and 5.2% for Group 3. Group 3 had a significantly higher incidence of MACCE than Group 1 (Group 1: hazard ratio [HR] = 1.46, 95% confidence interval [CI] = 1.32–1.62; Group 2: HR = 1.27, 95% CI = 1.17–1.37). In the model adjusted for age, sex, comorbidities, income level, body mass index, smoking, and drinking status, the MACCE risk was 1.25 times higher in Group 3 than Group 1 (95% CI = 1.13–1.40). Conclusions The degree of height loss was independently associated with CVD occurrences in the Korean population.
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Moon et al. (2022) conducted a cohort in Cardiovascular disease (n=127,573). Height loss ≥0.6 cm/year vs. Height loss 0 to <0.3 cm/year was evaluated on MACCE (HR 1.25, 95% CI 1.13-1.40). Annual height loss of ≥0.6 cm was independently associated with a higher risk of MACCE compared to height loss of <0.3 cm (adjusted HR 1.25; 95% CI 1.13-1.40).
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