Key result
An off-label spinal MRI in a patient with generalized dystonia and 4 DBS electrodes resulted in no adverse effects, suggesting manufacturer guidelines may be overly restrictive.
Why the study?
MRI in patients with implanted DBS systems is subject to strict safety guidelines, including limits on the number of implanted leads.
Does off-label spinal MRI cause adverse effects in a patient with 4 DBS electrodes and 2 implantable pulse generators?
Case Report (n=1)
Does off-label spinal MRI cause adverse effects in a patient with 4 DBS electrodes and 2 implantable pulse generators?
Off-label spinal MRI was performed safely without adverse effects in a patient with multiple DBS systems, suggesting current manufacturer guidelines may be overly restrictive.
Answers are grounded in this paper and cite their sources.
Safe off-label spinal MRI occurred without harm in multi-lead DBS; leaves open guideline revision pending prospective data.
Magnetic resonance imaging (MRI) in patients with implanted deep brain stimulation (DBS) systems is subject to strict guidelines in order to ensure patient safety. Criteria include limits on the number of implanted leads. Here, we describe the case of a 29-year-old patient with generalized dystonia implanted with 4 DBS electrodes and 2 implantable pulse generators, who had an off-label spinal MRI without regard for manufacturer guidance yet suffered no adverse effects. This suggests that manufacturer guidelines might be overly restrictive with regards to limits on implanted DBS hardware. Further research in this area is needed to widen access to this fundamental imaging modality for patients with DBS.
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Hayley et al. (2022) conducted a case report in Generalized dystonia (n=1). Off-label spinal MRI was evaluated on Adverse effects. An off-label spinal MRI in a patient with generalized dystonia and 4 DBS electrodes resulted in no adverse effects, suggesting manufacturer guidelines may be overly restrictive.
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