Experimental observations reveal changes in muscle cell membrane excitability during tunicate development, indicating regenerative potential.
During the course of development of muscle cells in certain tunicates, a sign of regenerative membrane response appears in the gastrula stage. In the early tadpole larva, the action potential consists of a spike followed by a plateau. The latter-disappears in fully differentiated cells, conceivably in association with the establishment of delayed rectification.
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Takahashi et al. (1971) studied this question.
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