Key result
Among Sudanese individuals with diabetes, the prevalence of acute coronary syndrome was 5.44%, with hypertension significantly increasing the risk of acute coronary syndrome (OR 2.462).
Why the study?
What is the prevalence and what are the risk factors for acute coronary syndrome among Sudanese individuals with diabetes?
Cross-Sectional (n=496)
Yes
What is the prevalence and what are the risk factors for acute coronary syndrome among Sudanese individuals with diabetes?
Odds Ratio: 2.462 (95% CI 1.007–6.5)
p-value: p=0.039
ACS prevalence data in Sudanese DM patients inform local screening; leaves open causal risk factor validation in prospective studies.
BACKGROUND: Acute coronary syndrome (ACS) is common with diabetes. The aim of this study was to establish prevalence and risk factors for ACS among Sudanese individuals with diabetes mellitus (DM). METHODS: A descriptive cross-sectional study was conducted in Khartoum State and Atabra (North of Sudan). The data collection was performed through pretested questionnaire, in addition to measurement of lipid profile and HbA1c. RESULTS: Among the 496 respondents, 234 (48.4%) were males and only 15 of them had ACS, while 255 (51.6%) were females and 12 had ACS. Therefore, the prevalence of ACS was 5.44% (95% confidence interval (CI): 3.45-7.44%). The unadjusted risk factors for ACS were age (P = 0.0008864), duration of DM (P = 0.01105) and presence of hypertension (P = 0.0006021). The presence of albuminuria, gender, and body mass index (BMI) was not associated with ACS. In addition, parameters like HbA1c, high-density lipoprotein (HDL), triglyceride and low-density cholesterol (LDL) were also not associated with ACS. Logistic regression analysis showed that duration of diabetes (odds ratio (OR) for below 5 years' history of DM = 0.175 (95% CI for OR: 0.180 - 0.835), P = 0.04051) and hypertension (OR = 2.462 (95% CI for OR: 1.007 - 6.500), P = 0.039) were absolute risk factors for ACS. CONCLUSION: The prevalence of ACS is estimated to be 5.44%. ACS in Sudanese individuals with DM was associated with hypertension, increase in age and increase in duration of DM.
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Ahmed et al. (2017) conducted a cross-sectional in Diabetes Mellitus (n=496). Hypertension vs. No hypertension was evaluated on Acute coronary syndrome (OR 2.462, 95% CI 1.007-6.500, p=0.039). Among Sudanese individuals with diabetes, the prevalence of acute coronary syndrome was 5.44%, with hypertension significantly increasing the risk of acute coronary syndrome (OR 2.462).
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