What is the clinical evidence from this study?

Study design: Review. Population: LDL dyslipidemias.

August 24, 2011Journal of Lipid ResearchOpen Access

Mechanisms and genetic determinants regulating sterol absorption, circulating LDL levels, and sterol elimination: implications for classification and disease risk

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Key result

Integrating genetic data with biological processes of sterol metabolism provides important insights for the classification, diagnosis, and management of LDL dyslipidemias and sitosterolemia.

Design

Review

Authors

SCS. CalandraUniversity of Modena and Reggio Emilia PTPatrizia TarugiUniversity of Modena and Reggio Emilia HSHelen E. SpeedyMRC Prion Unit

Discussion

Member takes

Implication

Advances genetic insights into LDL dyslipidemias; leaves open targeted therapies pending prospective validation.

PICO

Population

LDL dyslipidemias

This review integrates genetic and biochemical insights into sterol metabolism to improve the classification and management of LDL dyslipidemias.

Cite This Study

Calandra et al. (2011) conducted a review in LDL dyslipidemias. Integrating genetic data with biological processes of sterol metabolism provides important insights for the classification, diagnosis, and management of LDL dyslipidemias and sitosterolemia.

synapsesocial.com/papers/6a6ba712547974b2dbf45bb8 https://doi.org/10.1194/jlr.r017855

View Full Paper

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Mechanisms and genetic determinants regulating sterol absorption, circulating LDL levels, and sterol elimination: implications for classification and disease risk

Discussion

Member takes

Implication

PICO

Cite This Study

Mechanisms and genetic determinants regulating sterol absorption, circulating LDL levels, and sterol elimination: implications for classification and disease risk

Discussion

Member takes

Implication

PICO

Cite This Study

Also Consider

Also Consider