to the higher activity b2-ADH in most Japanese. However, is not clearly understood. FPM seems unlikely to explain very much of the susceptibility of women to alcoholic liver disease. 6 the genotypes of Japanese for this ADH variant were not determined, and the faster ethanol metabolism in Japanese has not been consistently observed by other investigators. DAVID W. CRABB, M.D. Lastly, the magnitude of the increase in FPM seen with the Division of Gastroenterology and Hepatology higher ethanol concentration was approximately 60 mg/kg Indiana University Medical Center body weight for the Caucasians, but 120 mg/kg for the Japa-Indianapolis, IN nese. Because there was no difference in the activity of x-ADH between groups, why was there the two-fold difference
No takes yet. Share an insight, caveat, or question.
Pierre‐Alain Clavien (1997) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: