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August 24, 2004EpilepsiaOpen Access

Phenobarbital for the Treatment of Epilepsy in the 21st Century: A Critical Review

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Authors

PKPatrick KwanThe Royal Melbourne HospitalMBMartin J. BrodieWestern Infirmary

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Kwan et al. (2004) studied this question.

synapsesocial.com/papers/6a6bb69e2ef98b0efacb6970https://doi.org/10.1111/j.0013-9580.2004.12704.x
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Inhibition of phenobarbitone N‐glucosidation by valproate.1994 · 35 citations
  2. 2Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data2002 · 692 citations
  3. 3Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter Gene<i>ABCB1</i>2003 · 653 citations
  4. 4Direct activation of GABAA receptors by barbiturates in cultured rat hippocampal neurons.1996 · 188 citations