It has long been known, and confirmed by direct isolation experiments (Honda, 1922, 1923; Wada 1930), that small quantities of many amino-acids are normally excreted in the urine, but that their excretion in large amounts occurs only in rare pathological conditions. The term amino-aciduria is reserved for such cases. It was first described in acute yellow atrophy of the liver, where its onset 01 Vol.
C. E. Dent (Wed,) studied this question.