Key result
Admission stress-hyperglycemia independently predicted higher in-hospital mortality (HR 4.2) in non-diabetic patients with acute myocardial infarction, regardless of coronary anatomy.
Why the study?
The prognostic role of hyperglycemia in MIOCA is recognized, but data on MINOCA are lacking.
Does admission stress-hyperglycemia predict adverse short- and long-term outcomes in patients with acute myocardial infarction (MIOCA and MINOCA)?
Population
2431 patients admitted with acute myocardial infarction (MIOCA and MINOCA)
Comparison
Admission stress-hyperglycemia (admission glucose ≥ 140 mg/dL) vs no admission stress-hyperglycemia
Design
Multicenter prospective cohort study
Follow-up
3-year
Authors
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Highlights admission glucose as prognostic marker in non-diabetic AMI; leaves open whether intervention improves outcomes.
Cohort (n=2,431)
Yes
Does admission stress-hyperglycemia predict adverse short- and long-term outcomes in patients with acute myocardial infarction (MIOCA and MINOCA)?
Hazard Ratio: 4.2 (95% CI 1.9–9.5)
p-value: p=0.001
Admission stress-hyperglycemia is a strong predictor of adverse short- and long-term outcomes in both MIOCA and MINOCA patients, regardless of diabetes status.
Paolisso et al. (2021) conducted a cohort in Acute myocardial infarction (n=2,431). Admission stress-hyperglycemia vs. Normoglycemia was evaluated on In-hospital mortality in non-diabetic patients (HR 4.2, 95% CI 1.9-9.5, p=0.001). Admission stress-hyperglycemia independently predicted higher in-hospital mortality (HR 4.2) in non-diabetic patients with acute myocardial infarction, regardless of coronary anatomy.